Milk withdrawal change

Recent changes to the datasheet for Mamyzin® mean that the milk withdrawal is reduced from 108 hours to 96 hours and the dose is now 15 mg/kg for three consecutive days.

Kath Aplin, veterinary adviser for Boehringer Ingelheim Animal Health, says: “The new dosage regimen gives clearer guidance to vets and their clients; a 660kg cow should receive 10g of penethamate hydriodide (one vial) daily for three days.

Mamyzin, a lecithin coated pro-drug of benzyl penicillin, is highly lipophilic and actively concentrates in the udder, where it is capable of entering epithelial cells to achieve intracellular bacterial kill. It provides targeted, narrow spectrum treatment for gram positive mastitis in situations where injectable therapy for mastitis is required.”